Fig. 4: Gene regulatory network of BD basal ganglia by SCENIC analysis. | Translational Psychiatry

Fig. 4: Gene regulatory network of BD basal ganglia by SCENIC analysis.

From: Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia

Fig. 4

A−D Heatmaps showing the differential regulon activity of cell type-specific transcription factors between BD and control caudate, putamen, GP, and SN, respectively. Lower panels show violin plots of representative TF expression across different cell types between BD and control. E A summary table showing TFs shared by different basal ganglia nuclei with frequent targets of PDEs and ion channels.

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