Table 1 Characteristics of Patient Demographics, Behavior, and Medical History, Stratified by Clusters a.
Characteristic | Overall n = 9925 | Cluster A1 n = 1053 | Cluster A2 n = 1305 | Cluster A3 n = 600 | Cluster A4 n = 535 | Cluster B1 n = 1233 | Cluster B2 n = 562 | Cluster C1 n = 879 | Cluster C2 n = 242 | Cluster C3 n = 581 | Cluster D1 n = 390 | Cluster D2 n = 491 | Cluster E1 n = 95 | Cluster E2 n = 420 | Cluster E3 n = 280 | Cluster E4 n = 1259 | p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
gender = Female (%) | 6575 (66.2) | 656 (62.3) | 965 (73.9) | 410 (68.3) | 368 (68.8) | 857 (69.5) | 392 (69.8) | 624 (71.0) | 165 (68.2) | 393 (67.6) | 228 (58.5) | 289 (58.9) | 60 (63.2) | 248 (59.0) | 139 (49.6) | 781 (62.0) | < 0.001 |
age group (%) | < 0.001 | ||||||||||||||||
0–17 | 768 (7.7) | 469 (44.5) | 0 (0.0) | 38 (6.3) | 102 (19.1) | 0 (0.0) | 33 (5.9) | 11 (1.3) | 0 (0.0) | 6 (1.0) | 7 (1.8) | 95 (19.3) | 2 (2.1) | 0 (0.0) | 2 (0.7) | 3 (0.2) | |
18–35 | 2299 (23.2) | 583 (55.4) | 43 (3.3) | 218 (36.3) | 422 (78.9) | 194 (15.7) | 126 (22.4) | 92 (10.5) | 19 (7.9) | 78 (13.4) | 37 (9.5) | 311 (63.3) | 16 (16.8) | 5 (1.2) | 12 (4.3) | 143 (11.4) | |
36–59 | 4222 (42.5) | 1 (0.1) | 966 (74.0) | 313 (52.2) | 11 (2.1) | 624 (50.6) | 316 (56.2) | 418 (47.6) | 123 (50.8) | 326 (56.1) | 126 (32.3) | 82 (16.7) | 43 (45.3) | 70 (16.7) | 102 (36.4) | 701 (55.7) | |
>= 60 | 2636 (26.6) | 0 (0.0) | 296 (22.7) | 31 (5.2) | 0 (0.0) | 415 (33.7) | 87 (15.5) | 358 (40.7) | 100 (41.3) | 171 (29.4) | 220 (56.4) | 3 (0.6) | 34 (35.8) | 345 (82.1) | 164 (58.6) | 412 (32.7) | |
marital status (%) | < 0.001 | ||||||||||||||||
divorced | 432 (4.4) | 0 (0.0) | 126 (9.7) | 39 (6.5) | 0 (0.0) | 52 (4.2) | 26 (4.6) | 40 (4.6) | 10 (4.1) | 28 (4.8) | 13 (3.3) | 8 (1.6) | 4 (4.2) | 10 (2.4) | 8 (2.9) | 68 (5.4) | |
married | 6941 (69.9) | 18 (1.7) | 1088 (83.4) | 436 (72.7) | 217 (40.6) | 1110 (90.0) | 428 (76.2) | 728 (82.8) | 211 (87.2) | 482 (83.0) | 308 (79.0) | 179 (36.5) | 75 (78.9) | 340 (81.0) | 242 (86.4) | 1079 (85.7) | |
unknown | 16 (0.2) | 7 (0.7) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 1 (0.1) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 1 (1.1) | 0 (0.0) | 1 (0.4) | 3 (0.2) | |
single/unmarried | 2121 (21.4) | 1028 (97.6) | 14 (1.1) | 125 (20.8) | 317 (59.3) | 24 (1.9) | 93 (16.5) | 58 (6.6) | 12 (5.0) | 44 (7.6) | 32 (8.2) | 303 (61.7) | 10 (10.5) | 5 (1.2) | 9 (3.2) | 47 (3.7) | |
widowed | 415 (4.2) | 0 (0.0) | 77 (5.9) | 0 (0.0) | 0 (0.0) | 46 (3.7) | 15 (2.7) | 52 (5.9) | 9 (3.7) | 27 (4.6) | 37 (9.5) | 0 (0.0) | 5 (5.3) | 65 (15.5) | 20 (7.1) | 62 (4.9) | |
job status (%) | < 0.001 | ||||||||||||||||
civil servant | 911 (9.2) | 16 (1.5) | 165 (12.6) | 54 (9.0) | 38 (7.1) | 121 (9.8) | 53 (9.4) | 82 (9.3) | 21 (8.7) | 51 (8.8) | 39 (10.0) | 28 (5.7) | 9 (9.5) | 73 (17.4) | 39 (13.9) | 122 (9.7) | |
farmer | 1393 (14.0) | 38 (3.6) | 219 (16.8) | 93 (15.5) | 35 (6.5) | 241 (19.5) | 83 (14.8) | 142 (16.2) | 34 (14.0) | 132 (22.7) | 64 (16.4) | 43 (8.8) | 11 (11.6) | 31 (7.4) | 37 (13.2) | 190 (15.1) | |
freelancers | 474 (4.8) | 32 (3.0) | 56 (4.3) | 39 (6.5) | 23 (4.3) | 69 (5.6) | 44 (7.8) | 40 (4.6) | 8 (3.3) | 24 (4.1) | 11 (2.8) | 28 (5.7) | 3 (3.2) | 9 (2.1) | 9 (3.2) | 79 (6.3) | |
retired | 1371 (13.8) | 1 (0.1) | 189 (14.5) | 35 (5.8) | 1 (0.2) | 194 (15.7) | 67 (11.9) | 193 (22.0) | 66 (27.3) | 111 (19.1) | 107 (27.4) | 8 (1.6) | 17 (17.9) | 122 (29.0) | 73 (26.1) | 187 (14.9) | |
staff | 1258 (12.7) | 67 (6.4) | 204 (15.6) | 136 (22.7) | 77 (14.4) | 155 (12.6) | 80 (14.2) | 103 (11.7) | 34 (14.0) | 84 (14.5) | 38 (9.7) | 62 (12.6) | 12 (12.6) | 22 (5.2) | 25 (8.9) | 159 (12.6) | |
student | 1345 (13.6) | 753 (71.5) | 2 (0.2) | 73 (12.2) | 191 (35.7) | 7 (0.6) | 60 (10.7) | 29 (3.3) | 1 (0.4) | 11 (1.9) | 12 (3.1) | 179 (36.5) | 11 (11.6) | 0 (0.0) | 4 (1.4) | 12 (1.0) | |
unemployed | 842 (8.5) | 75 (7.1) | 103 (7.9) | 75 (12.5) | 51 (9.5) | 98 (7.9) | 49 (8.7) | 62 (7.1) | 29 (12.0) | 63 (10.8) | 36 (9.2) | 65 (13.2) | 12 (12.6) | 16 (3.8) | 7 (2.5) | 101 (8.0) | |
unknown | 1843 (18.6) | 62 (5.9) | 270 (20.7) | 70 (11.7) | 105 (19.6) | 268 (21.7) | 94 (16.7) | 177 (20.1) | 38 (15.7) | 80 (13.8) | 62 (15.9) | 57 (11.6) | 14 (14.7) | 131 (31.2) | 77 (27.5) | 338 (26.8) | |
worker | 488 (4.9) | 9 (0.9) | 97 (7.4) | 25 (4.2) | 14 (2.6) | 80 (6.5) | 32 (5.7) | 51 (5.8) | 11 (4.5) | 25 (4.3) | 21 (5.4) | 21 (4.3) | 6 (6.3) | 16 (3.8) | 9 (3.2) | 71 (5.6) | |
main diagnosis (%) | < 0.001 | ||||||||||||||||
Depression | 7738 (78.0) | 1053 (100) | 1305 (100) | 600 (100) | 535 (100) | 1231 (99.8) | 504 (89.7) | 692 (78.7) | 205 (84.7) | 534 (91.9) | 374 (95.9) | 296 (60.3) | 13 (13.7) | 21 (5.0) | 6 (2.1) | 369 (29.3) | |
Diseases of the circulatory system | 341 (3.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 30 (3.4) | 1 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 23 (24.2) | 109 (26.0) | 59 (21.1) | 118 (9.4) | |
Diseases of the digestive system | 74 (0.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (0.9) | 3 (1.2) | 2 (0.3) | 0 (0.0) | 0 (0.0) | 5 (5.3) | 9 (2.1) | 7 (2.5) | 40 (3.2) | |
Diseases of the musculoskeletal system | 154 (1.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 16 (1.8) | 1 (0.4) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 15 (15.8) | 23 (5.5) | 20 (7.1) | 78 (6.2) | |
Diseases of the nervous system | 378 (3.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 31 (3.5) | 1 (0.4) | 4 (0.7) | 0 (0.0) | 6 (1.2) | 3 (3.2) | 77 (18.3) | 75 (26.8) | 179 (14.2) | |
Diseases of the respiratory system | 122 (1.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 7 (0.8) | 5 (2.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (2.1) | 47 (11.2) | 21 (7.5) | 40 (3.2) | |
Mental and behavioral disorders due to psychoactive substance use | 91 (0.9) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 9 (1.0) | 6 (2.5) | 11 (1.9) | 6 (1.5) | 26 (5.3) | 0 (0.0) | 0 (0.0) | 4 (1.4) | 28 (2.2) | |
Neoplasms | 70 (0.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (0.9) | 1 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 14 (14.7) | 12 (2.9) | 4 (1.4) | 31 (2.5) | |
Neurotic, stress-related and somatoform disorders | 334 (3.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 49 (8.7) | 27 (3.1) | 9 (3.7) | 26 (4.5) | 8 (2.1) | 79 (16.1) | 1 (1.1) | 10 (2.4) | 5 (1.8) | 119 (9.5) | |
Organic/symptomatic mental disorders | 43 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 6 (0.7) | 1 (0.4) | 0 (0.0) | 1 (0.3) | 2 (0.4) | 0 (0.0) | 17 (4.0) | 5 (1.8) | 11 (0.9) | |
other | 477 (4.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 39 (4.4) | 6 (2.5) | 0 (0.0) | 0 (0.0) | 20 (4.1) | 18 (18.9) | 94 (22.4) | 74 (26.4) | 225 (17.9) | |
Other mental and behavioral disorders | 72 (0.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 4 (0.7) | 5 (0.6) | 2 (0.8) | 3 (0.5) | 1 (0.3) | 44 (9.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 12 (1.0) | |
Schizophrenia, schizotypal and delusional disorders | 31 (0.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 1 (0.4) | 1 (0.2) | 0 (0.0) | 17 (3.5) | 1 (1.1) | 1 (0.2) | 0 (0.0) | 9 (0.7) | |
total number of diagnoses (%) | < 0.001 | ||||||||||||||||
1 | 3901 (39.3) | 914 (86.8) | 1098 (84.1) | 509 (84.8) | 488 (91.2) | 649 (52.6) | 236 (42.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 7 (7.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
2 | 2150 (21.7) | 108 (10.3) | 148 (11.3) | 57 (9.5) | 38 (7.1) | 314 (25.5) | 169 (30.1) | 242 (27.5) | 0 (0.0) | 157 (27.0) | 83 (21.3) | 363 (73.9) | 11 (11.6) | 0 (0.0) | 0 (0.0) | 460 (36.5) | |
3 | 1261 (12.7) | 25 (2.4) | 47 (3.6) | 23 (3.8) | 7 (1.3) | 150 (12.2) | 82 (14.6) | 236 (26.8) | 25 (10.3) | 176 (30.3) | 87 (22.3) | 95 (19.3) | 15 (15.8) | 30 (7.1) | 15 (5.4) | 248 (19.7) | |
4 | 768 (7.7) | 2 (0.2) | 7 (0.5) | 8 (1.3) | 2 (0.4) | 58 (4.7) | 41 (7.3) | 160 (18.2) | 45 (18.6) | 111 (19.1) | 59 (15.1) | 28 (5.7) | 19 (20.0) | 46 (11.0) | 34 (12.1) | 148 (11.8) | |
5 | 584 (5.9) | 2 (0.2) | 4 (0.3) | 3 (0.5) | 0 (0.0) | 39 (3.2) | 24 (4.3) | 98 (11.1) | 55 (22.7) | 79 (13.6) | 57 (14.6) | 4 (0.8) | 14 (14.7) | 57 (13.6) | 45 (16.1) | 103 (8.2) | |
6 | 433 (4.4) | 2 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 10 (0.8) | 6 (1.1) | 71 (8.1) | 42 (17.4) | 29 (5.0) | 40 (10.3) | 1 (0.2) | 8 (8.4) | 88 (21.0) | 47 (16.8) | 89 (7.1) | |
7 | 828 (8.3) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 13 (1.1) | 4 (0.7) | 72 (8.2) | 75 (31.0) | 29 (5.0) | 64 (16.4) | 0 (0.0) | 21 (22.1) | 199 (47.4) | 139 (49.6) | 211 (16.8) | |
severity (%) | < 0.001 | ||||||||||||||||
mild | 1 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | |
moderate | 12 (0.1) | 1 (0.1) | 1 (0.1) | 2 (0.3) | 0 (0.0) | 1 (0.1) | 1 (0.2) | 0 (0.0) | 1 (0.4) | 2 (0.3) | 1 (0.3) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 1 (0.4) | 0 (0.0) | |
Other | 4 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 2 (0.2) | |
severe | 1847 (18.6) | 431 (40.9) | 12 (0.9) | 598 (99.7) | 2 (0.4) | 58 (4.7) | 133 (23.7) | 129 (14.7) | 48 (19.8) | 122 (21.0) | 50 (12.8) | 201 (40.9) | 12 (12.6) | 4 (1.0) | 3 (1.1) | 44 (3.5) | |
unspecified | 8061 (81.2) | 621 (59.0) | 1292 (99.0) | 0 (0.0) | 533 (99.6) | 1173 (95.1) | 428 (76.2) | 750 (85.3) | 193 (79.8) | 457 (78.7) | 339 (86.9) | 289 (58.9) | 83 (87.4) | 415 (98.8) | 276 (98.6) | 1212 (96.3) | |
comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 3901 (39.3) | 914 (86.8) | 1098 (84.1) | 509 (84.8) | 488 (91.2) | 649 (52.6) | 236 (42.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 7 (7.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
TRUE | 6024 (60.7) | 139 (13.2) | 207 (15.9) | 91 (15.2) | 47 (8.8) | 584 (47.4) | 326 (58.0) | 879 (100.0) | 242 (100.0) | 581 (100.0) | 390 (100.0) | 491 (100.0) | 88 (92.6) | 420 (100.0) | 280 (100.0) | 1259 (100) | |
psychiatric comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 6690 (67.4) | 1053 (100) | 1305 (100) | 600 (100.0) | 535 (100.0) | 1205 (97.7) | 387 (68.9) | 614 (69.9) | 178 (73.6) | 454 (78.1) | 331 (84.9) | 0 (0.0) | 12 (12.6) | 4 (1.0) | 0 (0.0) | 12 (1.0) | |
TRUE | 3235 (32.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 28 (2.3) | 175 (31.1) | 265 (30.1) | 64 (26.4) | 127 (21.9) | 59 (15.1) | 491 (100.0) | 83 (87.4) | 416 (99.0) | 280 (100.0) | 1247 (99.0) | |
endocrine comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 8218 (82.8) | 1047 (99.4) | 1305 (100) | 600 (100) | 535 (100.0) | 1233 (100) | 510 (90.7) | 0 (0.0) | 0 (0.0) | 581 (100.0) | 291 (74.6) | 466 (94.9) | 74 (77.9) | 273 (65.0) | 198 (70.7) | 1105 (87.8) | |
TRUE | 1707 (17.2) | 6 (0.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 52 (9.3) | 879 (100.0) | 242 (100.0) | 0 (0.0) | 99 (25.4) | 25 (5.1) | 21 (22.1) | 147 (35.0) | 82 (29.3) | 154 (12.2) | |
nervous comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 9243 (93.1) | 1053 (100) | 1305 (100) | 600 (100.0) | 535 (100.0) | 1233 (100) | 561 (99.8) | 879 (100.0) | 241 (99.6) | 580 (99.8) | 0 (0.0) | 491 (100.0) | 87 (91.6) | 420 (100.0) | 0 (0.0) | 1258 (99.9) | |
TRUE | 682 (6.9) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 1 (0.4) | 1 (0.2) | 390 (100.0) | 0 (0.0) | 8 (8.4) | 0 (0.0) | 280 (100.0) | 1 (0.1) | |
digestive comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 8532 (86.0) | 1030 (97.8) | 1305 (100) | 600 (100.0) | 535 (100.0) | 1232 (99.9) | 487 (86.7) | 878 (99.9) | 4 (1.7) | 0 (0.0) | 313 (80.3) | 491 (100.0) | 75 (78.9) | 419 (99.8) | 223 (79.6) | 940 (74.7) | |
TRUE | 1393 (14.0) | 23 (2.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 75 (13.3) | 1 (0.1) | 238 (98.3) | 581 (100.0) | 77 (19.7) | 0 (0.0) | 20 (21.1) | 1 (0.2) | 57 (20.4) | 319 (25.3) | |
circulatory comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 7802 (78.6) | 1049 (99.6) | 1305 (100) | 599 (99.8) | 533 (99.6) | 797 (64.6) | 484 (86.1) | 572 (65.1) | 149 (61.6) | 482 (83.0) | 227 (58.2) | 480 (97.8) | 59 (62.1) | 0 (0.0) | 120 (42.9) | 946 (75.1) | |
TRUE | 2123 (21.4) | 4 (0.4) | 0 (0.0) | 1 (0.2) | 2 (0.4) | 436 (35.4) | 78 (13.9) | 307 (34.9) | 93 (38.4) | 99 (17.0) | 163 (41.8) | 11 (2.2) | 36 (37.9) | 420 (100.0) | 160 (57.1) | 313 (24.9) | |
respiratory comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 9070 (91.4) | 1024 (97.2) | 1270 (97.3) | 586 (97.7) | 527 (98.5) | 1153 (93.5) | 539 (95.9) | 787 (89.5) | 215 (88.8) | 514 (88.5) | 329 (84.4) | 475 (96.7) | 82 (86.3) | 283 (67.4) | 210 (75.0) | 1076 (85.5) | |
TRUE | 855 (8.6) | 29 (2.8) | 35 (2.7) | 14 (2.3) | 8 (1.5) | 80 (6.5) | 23 (4.1) | 92 (10.5) | 27 (11.2) | 67 (11.5) | 61 (15.6) | 16 (3.3) | 13 (13.7) | 137 (32.6) | 70 (25.0) | 183 (14.5) | |
cancer comorbidity (%) | < 0.001 | ||||||||||||||||
FALSE | 9831 (99.1) | 1052 (99.9) | 1300 (99.6) | 600 (100.0) | 534 (99.8) | 1228 (99.6) | 560 (99.6) | 865 (98.4) | 240 (99.2) | 577 (99.3) | 389 (99.7) | 490 (99.8) | 92 (96.8) | 400 (95.2) | 275 (98.2) | 1229 (97.6) | |
TRUE | 94 (0.9) | 1 (0.1) | 5 (0.4) | 0 (0.0) | 1 (0.2) | 5 (0.4) | 2 (0.4) | 14 (1.6) | 2 (0.8) | 4 (0.7) | 1 (0.3) | 1 (0.2) | 3 (3.2) | 20 (4.8) | 5 (1.8) | 30 (2.4) | |
total number of surgeries (%) | < 0.001 | ||||||||||||||||
0 | 9292 (93.6) | 1040 (98.8) | 1302 (99.8) | 596 (99.3) | 534 (99.8) | 1221 (99.0) | 557 (99.1) | 857 (97.5) | 227 (93.8) | 563 (96.9) | 380 (97.4) | 490 (99.8) | 0 (0.0) | 397 (94.5) | 214 (76.4) | 914 (72.6) | |
1 | 544 (5.5) | 13 (1.2) | 3 (0.2) | 4 (0.7) | 1 (0.2) | 12 (1.0) | 5 (0.9) | 22 (2.5) | 14 (5.8) | 18 (3.1) | 10 (2.6) | 1 (0.2) | 44 (46.3) | 23 (5.5) | 65 (23.2) | 309 (24.5) | |
2 | 59 (0.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 21 (22.1) | 0 (0.0) | 1 (0.4) | 36 (2.9) | |
3 | 13 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 13 (13.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
4 | 2 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (2.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
5 | 15 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 15 (15.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
history of smoking (%) | < 0.001 | ||||||||||||||||
FALSE | 9480 (95.5) | 1052 (99.9) | 1302 (99.8) | 600 (100.0) | 535 (100.0) | 1217 (98.7) | 562 (100.0) | 836 (95.1) | 234 (96.7) | 572 (98.5) | 380 (97.4) | 486 (99.0) | 73 (76.8) | 327 (77.9) | 216 (77.1) | 1088 (86.4) | |
TRUE | 445 (4.5) | 1 (0.1) | 3 (0.2) | 0 (0.0) | 0 (0.0) | 16 (1.3) | 0 (0.0) | 43 (4.9) | 8 (3.3) | 9 (1.5) | 10 (2.6) | 5 (1.0) | 22 (23.2) | 93 (22.1) | 64 (22.9) | 171 (13.6) | |
history of drinking (%) | < 0.001 | ||||||||||||||||
FALSE | 9594 (96.7) | 1052 (99.9) | 1302 (99.8) | 598 (99.7) | 535 (100.0) | 1221 (99.0) | 560 (99.6) | 841 (95.7) | 235 (97.1) | 572 (98.5) | 382 (97.9) | 487 (99.2) | 83 (87.4) | 367 (87.4) | 231 (82.5) | 1128 (89.6) | |
TRUE | 331 (3.3) | 1 (0.1) | 3 (0.2) | 2 (0.3) | 0 (0.0) | 12 (1.0) | 2 (0.4) | 38 (4.3) | 7 (2.9) | 9 (1.5) | 8 (2.1) | 4 (0.8) | 12 (12.6) | 53 (12.6) | 49 (17.5) | 131 (10.4) | |
history of medication use (%) | <0.001 | ||||||||||||||||
none | 7846 (79.1) | 950 (90.2) | 951 (72.9) | 498 (83.0) | 465 (86.9) | 919 (74.5) | 435 (77.4) | 638 (72.6) | 161 (66.5) | 436 (75.0) | 281 (72.1) | 379 (77.2) | 83 (87.4) | 363 (86.4) | 251 (89.6) | 1036 (82.3) | |
often | 1546 (15.6) | 56 (5.3) | 258 (19.8) | 58 (9.7) | 42 (7.9) | 242 (19.6) | 92 (16.4) | 205 (23.3) | 67 (27.7) | 113 (19.4) | 88 (22.6) | 73 (14.9) | 8 (8.4) | 49 (11.7) | 25 (8.9) | 170 (13.5) | |
sometime | 533 (5.4) | 47 (4.5) | 96 (7.4) | 44 (7.3) | 28 (5.2) | 72 (5.8) | 35 (6.2) | 36 (4.1) | 14 (5.8) | 32 (5.5) | 21 (5.4) | 39 (7.9) | 4 (4.2) | 8 (1.9) | 4 (1.4) | 53 (4.2) | |
total number of core symptoms (%) | < 0.001 | ||||||||||||||||
0 | 3133 (31.6) | 149 (14.2) | 222 (17.0) | 66 (11.0) | 55 (10.3) | 226 (18.3) | 139 (24.7) | 274 (31.2) | 76 (31.4) | 128 (22.0) | 110 (28.2) | 129 (26.3) | 75 (78.9) | 384 (91.4) | 261 (93.2) | 839 (66.6) | |
1 | 5712 (57.6) | 736 (69.9) | 914 (70.0) | 437 (72.8) | 385 (72.0) | 777 (63.0) | 386 (68.7) | 521 (59.3) | 148 (61.2) | 394 (67.8) | 239 (61.3) | 333 (67.8) | 16 (16.8) | 29 (6.9) | 17 (6.1) | 380 (30.2) | |
2 | 1080 (10.9) | 168 (16.0) | 169 (13.0) | 97 (16.2) | 95 (17.8) | 230 (18.7) | 37 (6.6) | 84 (9.6) | 18 (7.4) | 59 (10.2) | 41 (10.5) | 29 (5.9) | 4 (4.2) | 7 (1.7) | 2 (0.7) | 40 (3.2) | |
total number of psychological symptoms (%) | <0.001 | ||||||||||||||||
0 | 6963 (70.2) | 667 (63.3) | 1008 (77.2) | 390 (65.0) | 373 (69.7) | 881 (71.5) | 0 (0.0) | 638 (72.6) | 186 (76.9) | 447 (76.9) | 279 (71.5) | 349 (71.1) | 81 (85.3) | 377 (89.8) | 248 (88.6) | 1039 (82.5) | |
1 | 2234 (22.5) | 329 (31.2) | 263 (20.2) | 195 (32.5) | 143 (26.7) | 305 (24.7) | 161 (28.6) | 199 (22.6) | 48 (19.8) | 118 (20.3) | 81 (20.8) | 109 (22.2) | 12 (12.6) | 41 (9.8) | 29 (10.4) | 201 (16.0) | |
2 | 676 (6.8) | 53 (5.0) | 33 (2.5) | 15 (2.5) | 19 (3.6) | 47 (3.8) | 360 (64.1) | 41 (4.7) | 8 (3.3) | 16 (2.8) | 29 (7.4) | 31 (6.3) | 2 (2.1) | 1 (0.2) | 2 (0.7) | 19 (1.5) | |
3 | 50 (0.5) | 4 (0.4) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 39 (6.9) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 1 (0.3) | 2 (0.4) | 0 (0.0) | 1 (0.2) | 1 (0.4) | 0 (0.0) | |
4 | 2 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
total number of physical symptoms (%) | <0.001 | ||||||||||||||||
0 | 4006 (40.4) | 952 (90.4) | 28 (2.1) | 179 (29.8) | 0 (0.0) | 630 (51.1) | 193 (34.3) | 310 (35.3) | 77 (31.8) | 136 (23.4) | 108 (27.7) | 319 (65.0) | 62 (65.3) | 258 (61.4) | 158 (56.4) | 596 (47.3) | |
1 | 4141 (41.7) | 96 (9.1) | 743 (56.9) | 345 (57.5) | 425 (79.4) | 475 (38.5) | 258 (45.9) | 377 (42.9) | 122 (50.4) | 289 (49.7) | 197 (50.5) | 142 (28.9) | 28 (29.5) | 120 (28.6) | 91 (32.5) | 433 (34.4) | |
2 | 1445 (14.6) | 5 (0.5) | 406 (31.1) | 71 (11.8) | 103 (19.3) | 104 (8.4) | 91 (16.2) | 153 (17.4) | 32 (13.2) | 130 (22.4) | 70 (17.9) | 29 (5.9) | 5 (5.3) | 36 (8.6) | 26 (9.3) | 184 (14.6) | |
3 | 300 (3.0) | 0 (0.0) | 110 (8.4) | 5 (0.8) | 7 (1.3) | 23 (1.9) | 18 (3.2) | 34 (3.9) | 10 (4.1) | 22 (3.8) | 14 (3.6) | 1 (0.2) | 0 (0.0) | 6 (1.4) | 5 (1.8) | 45 (3.6) | |
4 | 32 (0.3) | 0 (0.0) | 18 (1.4) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 2 (0.4) | 4 (0.5) | 1 (0.4) | 4 (0.7) | 1 (0.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | |
5 | 1 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
vital signs, median (IQR) | |||||||||||||||||
body temperature | 36.50 [36.40,36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.60 [36.50, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.60] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.40, 36.70] | 36.50 [36.30, 36.70] | 36.50 [36.30, 36.60] | 36.50 [36.30, 36.70] | 36.50 [36.30, 36.70] | < 0.001 |
pulse | 80.00 [72.00, 88.00] | 80.00 [76.00, 90.00] | 80.00 [72.00, 86.00] | 80.00 [75.00, 90.00] | 80.00 [76.00, 89.00] | 80.00 [72.00, 87.00] | 80.00 [72.00, 87.75] | 80.00 [73.00, 87.00] | 80.00 [75.00, 89.00] | 80.00 [71.00, 88.00] | 80.00 [74.00, 87.00] | 80.00 [72.00, 90.00] | 78.00 [68.00, 84.50] | 80.00 [70.00, 85.00] | 78.00 [70.75, 86.25] | 80.00 [72.00, 88.00] | < 0.001 |
breath | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [20.00, 20.00] | 20.00 [19.00, 20.00] | 20.00 [19.75, 20.00] | 20.00 [20.00, 20.00] | 0.005 |
SBP | 120.00 [111.00, 132.00] | 116.00 [109.00, 122.00] | 120.00 [111.00, 130.00] | 120.00 [111.00, 126.00] | 115.00 [108.00, 121.00] | 122.00 [112.00, 136.00] | 120.00 [110.00, 132.00] | 125.00 [114.00, 138.00] | 125.00 [117.25, 138.75] | 120.00 [113.00, 132.00] | 126.00 [115.25, 137.00] | 115.00 [108.00, 124.00] | 120.00 [110.00, 130.00] | 130.00 [120.00, 146.00] | 128.50 [117.00, 143.00] | 123.00 [112.00, 136.00] | < 0.001 |
DBP | 77.00 [70.00, 84.00] | 76.00 [68.00, 80.00] | 76.00 [70.00, 83.00] | 77.00 [71.00, 84.00] | 75.00 [69.00, 82.00] | 77.00 [70.00, 85.00] | 77.00 [70.00, 84.00] | 77.00 [70.00, 85.00] | 78.00 [73.25, 85.00] | 77.00 [70.00, 85.00] | 76.00 [70.25, 84.00] | 76.00 [68.00, 82.00] | 74.00 [64.50, 82.00] | 77.50 [70.00, 86.00] | 79.00 [72.00, 86.00] | 78.00 [70.00, 85.00] | < 0.001 |
admission age, median (IQR) | 46.00 [31.00, 60.00] | 18.00 [16.00, 22.00] | 49.00 [42.00, 59.00] | 38.00 [29.00, 46.00] | 25.00 [19.00, 31.00] | 50.00 [40.00, 64.00] | 44.00 [33.00, 55.00] | 56.00 [45.00, 65.00] | 56.00 [46.00, 65.00] | 50.00 [40.00, 61.00] | 63.00 [48.00, 72.00] | 25.00 [19.00, 33.00] | 52.00 [39.50, 64.50] | 73.00 [63.00, 79.00] | 64.50 [51.75, 74.00] | 51.00 [43.00, 63.00] | < 0.001 |
length of stay, median (IQR) | 15.00 [11.00, 21.00] | 15.00 [11.00, 21.00] | 16.00 [13.00, 21.00] | 16.00 [12.00, 21.00] | 14.00 [11.00, 19.00] | 17.00 [12.00, 22.00] | 17.00 [13.00, 21.75] | 17.00 [11.00, 22.50] | 18.00 [13.00, 24.75] | 16.00 [13.00, 22.00] | 18.00 [13.00, 25.00] | 16.00 [12.00, 22.00] | 14.00 [9.50, 23.50] | 12.00 [8.00, 21.00] | 12.00 [8.00, 20.00] | 13.00 [8.00, 19.00] | < 0.001 |
