Fig. 3: Remote PBM ameliorates neuronal apoptosis and degeneration caused by rCHI. | Translational Psychiatry

Fig. 3: Remote PBM ameliorates neuronal apoptosis and degeneration caused by rCHI.

From: Remote photobiomodulation ameliorates behavioral and neuropathological outcomes in a rat model of repeated closed head injury

Fig. 3

A Representative immunofluorescence images of co-staining of NeuN and TUNEL. Line-scan analysis was utilized to assess co-localization. Statistical analysis depicting the number of TUNEL and NeuN positive cells in the cortex and hippocampus. B Representative immunofluorescence images showing co-staining of NeuN and cleaved-caspase 3. Co-localization analysis of NeuN and cleaved-caspase 3 and statistical quantification of cleaved-caspase 3 immunofluorescence intensity. C Representative immunofluorescence images demonstrating co-staining of NeuN and cleaved-caspase 9. Co-localization analysis of NeuN and cleaved-caspase 9 and statistical quantification of cleaved-caspase 9 immunofluorescence intensity. D Representative immunofluorescence images displaying co-staining of NeuN and Fluoro-Jade C. Co-localization analysis of NeuN and Fluoro-Jade C and the number of Fluoro-Jade C-positive neurons. Scale bar = 10 μM. Data are presented as mean ± SEM. *P < 0.05 versus Cont group, #P < 0.05 versus rCHI group. ns indicates no significant differences. AU arbitrary unit.

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