Table 2 Risk of incident cognitive impairment according to the changing trend of RLLCa.
Changing trend of RLLC | ||||
---|---|---|---|---|
Stable healthyd | Positively adjustede | Negatively adjustedf | Stable unhealthyg | |
Incident cognitive impairment | ||||
No. of cases | 103 | 6 | 282 | 156 |
Person-years | 1189 | 191 | 783 | 654 |
Cases per 1000 person-years | 86.63 | 31.41 | 360.15 | 238.53 |
Minimally adjusted modelb | ||||
HR (95% CI) | 0.45 (0.34, 0.61) | 0.16 (0.07, 0.35) | 1.55 (1.27, 1.89) | 1 [Reference] |
P value | <0.001 | <0.001 | <0.001 | |
Fully adjusted modelc | ||||
HR (95% CI) | 0.46 (0.34, 0.62) | 0.16 (0.07, 0.35) | 1.55 (1.27, 1.90) | 1 [Reference] |
P value | <0.001 | <0.001 | <0.001 |