Fig. 5: Reversal of sex differences in psychosis.
From: Sex and regional differences in gene expression across the striatum in psychosis
A, B Heat maps of biological process enrichment from AW-Fisher meta-analyses. Two meta-analyses were performed, one for the effects of psychosis in each sex (psychosis vs control in each sex; left column of each heat map) and one for sex differences (male vs female in each disease group; right column of each heatmap). Heat maps in A and B show the overlap in biological processes between the meta-analyses, with distinct patterns for each heat map. C Scatterplots of a representative gene (IL1R1) in the caudate from the MāāāFā psychosis disease meta-analysis in heat map A. This gene is plotted a different way in the right panel with male and female grouped together to show the reversal in sex differences. D Scatterplots of a representative gene (TMEM52B) in the caudate from the MāāāFā psychosis disease meta-analysis in heat map B. This gene is plotted a different way in the right panel with male and female grouped together to show the reversal in sex differences.
