Fig. 2: Schematic overview of the study design.

Schematic overview of association analyses of highly pleiotropic (i.e., associated with at least four neuropsychiatric disorders) and predominantly SCZ-associated GRS/SNPs with brain structure and outcomes related to mental health. GRS genetic risk score, GWAS genome-wide association study, IDP image-derived phenotypes, PGC Psychiatric Genomics Consortium, pred. predominantly, SCZ schizophrenia, SNP single-nucleotide polymorphism.