Fig. 3: Association between the genetic risk scores and structural brain phenotypes in the UK biobank cohort. | Translational Psychiatry

Fig. 3: Association between the genetic risk scores and structural brain phenotypes in the UK biobank cohort.

From: Neurobiological correlates of schizophrenia-specific and highly pleiotropic genetic risk scores for neuropsychiatric disorders

Fig. 3

Associations between the brain volume (left column), cortical thickness (CT, middle column), and surface area (SA, right column) and A the genetic risk score of 22 highly pleiotropic SNPs (PleioPsych-GRS) and B the genetic risk score of 21 predominantly SCZ-associated SNPs (SCZ-GRS). Associations with puncorrected < 0.01 are depicted. Red color denotes positive, whereas blue color denotes negative, standardized beta coefficients. CT cortical thickness, GRS genetic risk score, SA surface area, SCZ schizophrenia.

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