Fig. 2: Cre-recombinase expression is postnatally delayed in pOxr1-Cre mice. | Translational Psychiatry

Fig. 2: Cre-recombinase expression is postnatally delayed in pOxr1-Cre mice.

From: Entorhinal cortex layer III Adgrl2 expression controls topographical circuit connectivity required for sequence learning

Fig. 2

(A) Representative confocal image of P10 (left) and P30 (right) horizontal brain section smFISH for MECIII marker Oxr1 (yellow) and MECII marker Reln (red). DAPI (blue) fluorescence shown for visualization of all nuclei. (Independent mice: n = 2 (1 female, 1 male) per timepoint) (B) Transgenic pOxr1-Cre and tdTomato Cre-reporter mice (Ai14) were crossed, and progeny positive for both alleles (pOxr1-Cre;Ai14) were analyzed during weekly timepoints during development (P7/P14/P21) and compared to adult (P50) tdTomato expression. Shown are representative images of multiple horizontal serial sections along the dorsal to ventral axis (Independent mice: P7 n = 3 (2 female, 1 male); P14 n = 2 (1 female, 1 male); P21 n = 4 (3 female, 1 male); p50 n = 1 male).

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