Table 1 Donor demographics and sample characteristics.

From: Lipidomic and proteomic insights from extracellular vesicles in the postmortem dorsolateral prefrontal cortex reveal substance use disorder-induced brain changes

SAB

Group

Ethnicity

Gender

Age

PMI (hours)

Cause of Death

Drugs at time of death

Overdose

Diagnosis

Tissue weight (mg)

67951

SUD

Black

Female

58

39.35

Toxic effect of cocaine

Cocaine, cocaethylene, benzoylecgonine, tetramisole

X

CUD

135

67968

SUD

Black

Female

45

13.07

Toxic effect of cocaine

Cocaine and metabolites

X

CUD

139

67958

SUD

White

Male

36

15.05

Toxic effects of heroin

6-monoacetylmorphine, morphine, codeine

X

OUD

161

67996

SUD

White

Female

36

24.47

Toxic effects of hydrocodone and morphine

Hydrocodone and morphine

X

OUD

126

79204

Control

Black

Female

45

26.40

Asthma

Negative

 

Control

119

79225

Control

Black

Female

69

20.32

Cardiovascular disease

Negative

 

Control

128

67976

Control

White

Female

69

24.82

Cardiovascular disease

Negative

 

Control

127

67992

Control

Black

Female

64

28.03

Cardiovascular disease

Negative

 

Control

139