Table 2 Mean costs, health effects, and ICERs of PAT using limited healthcare and societal perspectives.

Perspective	Intervention	Mean cost in US$ (95% PI)^a	Mean QALYs (95% PI)	Expected ICER^b
Healthcare	Standard of care	11,061 (10.162–11915)	0.540 (0.457–0.620)
	Psilocybin-assisted therapy	14,700 (13.914–15.474)	0.571 (0.489–0.649)	117,517
Societal	Standard of care	12,564 (11.572–13554)	0.540 (0.457–0.620)
	Psilocybin-assisted therapy	16,003 (15.090–16.896)	0.571 (0.489–0.649)	111,069

The 95% predicted intervals (PI) represent the 5 and 95th percentile of the 1000 probabilistic simulations conducted. Mean costs were rounded to the nearest dollar, and mean QALYs were rounded to three decimal places.
ICER incremental cost-effectiveness ratio, PI predicted interval, QALY quality-adjusted life year.
^aThe assumed cost of psilocybin-assisted therapy is $5000 per treatment.
^bICERs portray the incremental cost per QALY gained and were calculated by comparing psilocybin-assisted therapy to standard of care. ICERs presented here were calculated using unrounded mean costs and QALYs and may therefore result in some discrepancy.

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