Table 3 Lasso regressions.

From: Clinical response to a single-dose methylphenidate challenge is indicative of treatment response at two months in adults with ADHD

Improvement at two-month follow-up

cor

p

Equation

Improvement_BAARS_ina

−0.167

0.203

Improvement_BAARS_ina = 3.31 + 0.179 * BAARS_ina_baseline

Improvement_BAARS_hyp/imp

0.497

0.000

Improvement_BAARS_hyp/imp = −4.258 + 0.126 * BAARS_hyp/imp_acute response + 0.032 * Distance_acute_response + 0.525 * BAARS_hyp/imp_baseline + 0.033 * Age − 0.013 * Dose_fu + 0.061 * Handedness_score − 0.059 * Education_years + 0.022 * IQtot

Improvement_BAARS_tot

0.284

0.028

Improvement_BAARS_tot = 0.123 + 0.013 * Area_acute_response + 0.713 * Barkley_Ina_baseline + 0.247 * Barkley_tot_baseline − 1.065 * QbAct_baseline − 0.093 * Dose_fu + 0.177 * Handedness_score − 0.497 * Education_years + 0.083 * IQtot

Improvement_QbAct

0.126

0.337

Improvement_QbAct = 0.247 + 0.02 * QbAct_acute_response + 0.07 * QbImp_acute_response + 0.008 * Area_acute_response + 0.057 * Error_rate_acute_response + 0.22 * QbAct_baseline - 0.01 * Handedness_score + 0.007 * IQtot

Improvement_QbImp

0.484

0.000

Improvement_QbImp = −0.066 + 0.388 * QbImp_acute_response − 0.005 * Omissions_acute_response+ 0.047 * Error_rate_acute_response+ 0.024 * BAARS_Ina_baseline − 0.014 * BAARS_tot_baseline + 0.224 * QbImp_baseline - 0.092 * QbIna_baseline + 0.003 * Age + 0.007 * IQtot

Improvement_QbIna

0.698

0.000

Improvement_QbIna = −1.225 + 0.023 * BAARS_ina_acute_response + 0.311 * QbIna_acute_response + 0 * Microevents_acute_response + 0.013 * Omissions_acute_response + 0.12 * Error_rate_acute_response + 0.003 * RTvar_acute_response − 0.047 * QbImp_baseline - 0.01 * Age + 0.015 * IQtot

  1. The lasso regressions showed significant correlations between predicted and actual values for BAARS total and hyperactivity/impulsivity, and Qb impulsivity and inattention with small-medium to large-very large effect sizes. Statistically significant results are displayed in bold.
  2. Act activity, Cor correlation coefficient (r), Imp impulsivity, Ina inattention, fu follow-up, p p-value, Qb Quantitative behavior test.
Back to article page