Fig. 1: The changes of autism-like behaviors before and after LdIL-2 treatment in mice. | Translational Psychiatry

Fig. 1: The changes of autism-like behaviors before and after LdIL-2 treatment in mice.

From: LdIL-2 treatment in ASD: a novel immunotherapeutic approach targeting Th/Treg dysfunction and neuroinflammation

Fig. 1

(C57 was used as the healthy control) A LdIL-2 treatment prescription; B different courses of LdIL-2 to BTBR mice, n = 6; C different dosages of IL-2 to BTBR mice, n = 6; D three-chamber social test (N: null, S: stranger mouse); E compare of social approach preference index and social novelty preference index in C57, before and after LdIL-2 treatment BTBR mice, n = 8; F self-grooming time, n = 8; G sniffing time, n = 8; H marble burying, n = 8; I total travel distance and center grid dwell time, n = 8; J proportion of card arm time in the Y maze, n = 7. ***P < 0.001, **P < 0.01, *P < 0.05.

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