Fig. 3: EA-mediated improvement of PSD was comparable to that of fluoxetine.

A–D Behavioral effects of PSD mice treated with FLX for two weeks in OFT (A), FST (B), TST (C), and SPT (D). (one-way ANOVA test, N = 9–10 per group). E Representative rasters of spikes from putative excitatory neurons. Scale bar, 10 s. F The statistical analysis of the firing frequency of the putative excitatory neurons for each mouse. (one-way ANOVA test, N = 6–10 per group). G The statistical analysis of the firing frequency of the putative excitatory neurons for each unit. (Kruskal-Wallis test, N = 247 units). H The statistical analysis of the firing frequency of the putative inhibitory neurons for each mouse (one-way ANOVA test, N = 5 per group). I The statistical analysis of the firing frequency of the putative inhibitory neurons for each unit (Kruskal-Wallis test, N = 37 units). J The statistical analysis of power spectrum results in theta rhythms from the mPFC neurons (Kruskal-Wallis test, N = 5 per group). K The statistical analysis of power spectrum results in high gamma rhythms from the mPFC neurons (Kruskal-Wallis test, N = 5 per group). Data are presented as mean ± SEM. P values are set to *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.