Fig. 1: Gene expression analysis of microglia activation related markers in the dorsal hippocampus of male animals exposed to prenatal stress.

The mRNA levels for C3, C4b, CX3CR1, iNOS and CD68 were measured in control (CTRL) and prenatally stressed group (PNS) (a) or after the separation in vulnerable (VULN) and resilient (RES) (c). The z-score was calculated based on the mRNA levels of C3, C4b, CX3CR1, iNOS and CD68 genes considering whole PNS group (b) or after the separation in vulnerable (VULN) and resilient (RES) (d). Statistical analysis for panels a, b: t-test, *p < 0,05 and **p < 0,01 (n = 14 to 30 per group). Statistical analysis for panels c, d: one-way ANOVA, Tukey’s post hoc, *p < 0,05 (n = 9 to 19 per group). Data are expressed as mean ± SEM and individuals are represented as dots.