Fig. 2: FPI causes cognitive but not motor deficits in mice with an alcohol-drinking history. | Translational Psychiatry

Fig. 2: FPI causes cognitive but not motor deficits in mice with an alcohol-drinking history.

From: Traumatic brain injury exacerbates alcohol consumption and neuroinflammation with decline in cognition and cholinergic activity

Fig. 2

a Experimental timeline. b-e No significant changes were observed in total distance traveled (c), movement velocity (d), or time spent in the periphery of the open field chamber (e) after FPI. f-h In the NORT, FPI did not affect total distance traveled (g) or velocity of movement (h). i The percent of FPI-treated mice that visit the novel object first was less than that of sham controls, indicating a cognitive deficit. n.s. (not significant; c, d, e, g, h). *p < 0.05 (i). unpaired t-test (c, d, e, g, h, i).

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