Fig. 11: Wogonin attenuates cell death in type 1 diabetic mice. | Acta Pharmacologica Sinica

Fig. 11: Wogonin attenuates cell death in type 1 diabetic mice.

From: Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease

Fig. 11

a Western blot analysis of cleaved caspase-3, Bax, and Bcl-2 in mice kidney tissues. b TUNEL assay in mice kidney tissues. apoptotic cell, red; DAPI, blue. c Immunohistochemistry analysis of Bcl-2 in mice kidney tissues. Scale bar = 50 μm. Results represent mean ± SEM for 6–8 mice. ***P < 0.001 vs NC. ##P < 0.01, ###P < 0.001 vs STZ. Abbreviations: NC normal control, Wog wogonin, STZ streptozotocin

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