Fig. 3: Wogonin inhibits HG-induced apoptosis. | Acta Pharmacologica Sinica

Fig. 3: Wogonin inhibits HG-induced apoptosis.

From: Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease

Fig. 3

a Western blot analysis of cleaved caspase-3, Bax, and Bcl-2 in MPC5 cells. b Real-time PCR analysis of Bcl-2 in MPC5 cells. c Flow cytometry analysis of PI/Annexin V-stained MPC5 cells. d TUNEL assay for MPC5 cells. Scale bar = 50 μm. Results represent mean ± SEM of three independent experiments. ***P < 0.001 vs NC. ##P < 0.01, ###P < 0.001 vs HG. Abbreviations: HG high glucose, NC normal control, Wog wogonin

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