Fig. 3: DHC reduces systemic and vascular inflammation in vivo. | Acta Pharmacologica Sinica

Fig. 3: DHC reduces systemic and vascular inflammation in vivo.

From: Antiatherosclerotic effect of dehydrocorydaline on ApoE−/− mice: inhibition of macrophage inflammation

Fig. 3

a, b Plasma levels of TNFα and IL-1β in Western diet-fed ApoE−/− mice treated with vehicle or DHC for 12 weeks. n = 6–8 mice per group. c Relative mRNA levels of the proinflammatory genes TNFα, NLRP3, and IL-18 in aortas isolated from Western diet-fed ApoE−/− mice treated with vehicle or DHC for 1 week. n = 5 mice per group. The data are shown as the mean ± SEM. *P < 0.05, **P < 0.01 vs. vehicle.

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