Table 1 Significantly correlated genes from autophagy with NRP1 in human HCC samples

From: Hepatocellular carcinoma cells loss lenvatinib efficacy in vitro through autophagy and hypoxia response-derived neuropilin-1 degradation

Abbreviation

Full gene name

Pearson-CC

BCL2L1

BCL2 like 1

+0.60

MTMR3

Myotubularin-related protein 3

+0.60

RRAGB

Ras related GTP binding B

+0.60

CFLAR

CASP8 and FADD like apoptosis regulator

+0.58

AKT3

AKT serine/threonine kinase 3

+0.57

BCL2

BCL2 apoptosis regulator

+0.56

SH3GLB1

SH3 domain containing GRB2 like, endophilin B1

+0.55

MAPK3

Mitogen-activated protein kinase 3

+0.54

GABARAPL2

GABA type A receptor-associated protein like 2

+0.53

ATG16L1

Autophagy-related 16 like 1

+0.52

MAP2K1

Mitogen-activated protein kinase kinase 1

+0.51

RRAGA

Ras related GTP binding A

+0.51

TRAF6

TNF receptor associated factor 6

+0.51

WDR41

WD repeat domain 41

+0.51

ATG3

Autophagy-related 3

+0.50

IGBP1

Immunoglobulin binding protein 1

+0.50

MAP1LC3B

Microtubule associated protein 1 light chain 3 beta

+0.50

MAPK1

Mitogen-activated protein kinase 1

+0.50

PPP2CB

Protein phosphatase 2 catalytic subunit beta

+0.50

RAB7A

RAB7A, member RAS oncogene family

+0.49

SMCR8

SMCR8-C9orf72 complex subunit

+0.48

RAB1A

RAB1A, member RAS oncogene family

+0.47

RRAS

RAS related

+0.47

PIK3C3

Phosphatidylinositol 3-kinase catalytic subunit type 3

+0.46

TANK

TRAF family member associated NFκB activator

+0.46

UVRAG

UV radiation resistance associated

+0.45

TSC1

TSC complex subunit 1

+0.44

DAPK1

Death associated protein kinase 1

+0.42

EIF2AK3

Eukaryotic translation initiation factor 2 alpha kinase 3

+0.42

RRAGC

Ras related GTP binding C

+0.42

MAP1LC3B2

Microtubule associated protein 1 light chain 3 beta 2

+0.41

BECN1

Beclin 1

+0.40

DAPK3

Death associated protein kinase 3

+0.40

EIF2S1

Eukaryotic translation initiation factor 2 subunit alpha

+0.40

PIK3R4

Phosphatidylinositol 3-kinase regulatory subunit 4

+0.40

PDPK1

3-phosphoinositide dependent protein kinase 1

+0.39

PPP2CA

Protein phosphatase 2 catalytic subunit Alpha

+0.39

TBK1

TANK binding kinase 1

+0.39

HMGB1

High mobility group box 1

+0.38

ATG4B

Autophagy-related 4B

+0.36

ATG4C

Autophagy-related 4C

+0.36

ATG7

Autophagy-related 7

+0.36

PRKACB

Protein kinase cAMP-activated catalytic subunit beta

+0.36

ATG9A

Autophagy-related 9A

+0.35

RRAS2

RAS related 2

+0.35

ITPR1

Inositol 1,4,5-trisphosphate receptor type 1

+0.34

RHEB

Ras homolog, mTORC1 binding

+0.34

NRAS

NRAS proto-oncogene, GTPase

+0.33

STX17

Syntaxin 17

+0.33

ATG2B

Autophagy-related 2B

+0.32

KRAS

KRAS proto-oncogene, GTPase

+0.32

MAP3K7

Mitogen-activated protein kinase kinase kinase 7

+0.32

PRKCD

Protein kinase C delta

+0.32

ULK2

Unc-51 like autophagy activating kinase 2

+0.32

AKT1

AKT serine/threonine kinase 1

+0.31

ATG5

Autophagy-related 5

+0.31

GABARAP

GABA type A receptor-associated protein

+0.31

GABARAPL1

GABA type A receptor-associated protein like 1

+0.31

ZFYVE1

Zinc finger FYVE-type containing 1

+0.31

  1. Pearson-CC Pearson-coefficient correlation.