Fig. 3: HBB is the only specifically expressed gene in AC-sensitive mice, overlayed in DO mice and progenitor mice. | Acta Pharmacologica Sinica

Fig. 3: HBB is the only specifically expressed gene in AC-sensitive mice, overlayed in DO mice and progenitor mice.

From: HBB contributes to individualized aconitine-induced cardiotoxicity in mice via interfering with ABHD5/AMPK/HDAC4 axis

Fig. 3

a–c Show the results in DO mice(n = 9). d–f Show the results in progenitor mice (n = 5). a The Overlapping DEGs (Venn diagram) and DEGs (Heat map). b Nine signaling pathways were overlayed (Histogram) and among top 50 signaling pathways enriched (Venn diagram). c 96 of DEGs were overlayed (Venn diagram), and DEGs expression were validated (Heat maps). Then the interaction was analyzed (network diagram). d Overlapping DEGs (Venn diagram) and cluster analysis of DEGs (Heat maps). e The signaling pathways enriched (venn diagram) were overlayed and top of 5 overlayed pathways (histogram). f Overlapping DEGs (Venn diagram) and 14 overlayed DEGs expression were validated (Heat maps). KEGG and the interaction of 14 overlayed DEGs (network diagram) (fold change > 2).

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