Fig. 1: RFR exposure inhibited tumor progression and evoked immune response in a murine model of PMM. | Acta Pharmacologica Sinica

Fig. 1: RFR exposure inhibited tumor progression and evoked immune response in a murine model of PMM.

From: Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells

Fig. 1

a Flowchart of the experimental strategy. b Photograph of PMM-bearing lungs and numbers of PMM. n = 6, mean ± SD. c Kaplan–Meier survival curves of the mice in control and RFR groups. n = 8. d Photograph of PMM-bearing lungs and PMM count. n = 6, mean ± SD. e Kaplan–Meier survival curves of the mice in control and TEE groups. n = 8. f Pearson correlation diagram of all samples in the transcriptomics data. g PCA score plot of the transcriptomic profile in the control and RFR groups. h Volcano plots of DEGs between the control and RFR groups. i Top 20 enriched KEGG signaling pathways in upregulated DEGs. PMM pulmonary metastatic melanoma, TEE thermal environmental exposure, **P < 0.01.

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