Author Correction: Bufalin suppresses the migration and invasion of prostate cancer cells through HOTAIR, the sponge of miR-520b

Correction to: Acta Pharmacologica Sinica https://doi.org/10.1038/s41401-019-0234-8, published online 26 April 2019

In Fig. 1c, the representative Transwell images of DU145 and PC3 cells in the bufalin group appeared incorrectly due to the mishandling in manuscript preparation. All the authors agree on the correction of our negligence as providing the corrected images presented below. The corresponding statistics of the relative invasion rate in Fig. 1d have also been corrected. The authors declare that these corrections do not affect the results or conclusions of this paper. We apologize for any inconvenience caused to the journal and readers.

Fig. 1: Bufalin regulates the cell proliferation, migration and invasion of PCa cells.

a After exposure to various concentrations (0.05–10 μM) of bufalin for 24 h, the viability of DU145 and PC3 cells was assessed with a CCK-8 assay. The proliferation ratio decreased dose-dependently. b After incubation with half of the IC₅₀ of bufalin, the wound healing assay indicated that bufalin impaired wound healing; the results were almost half the value of the control group. c Transwell assays showed that the invasion rates of PCa cells decreased sharply in the bufalin-treated group. d Comparisons of the migration rates and relative invasion rates between the bufalin and control groups are shown (^*P < 0.05 compared with the control).

Corrected: