Table 2 Relevant upstream transcription regulators at 200, 500, and 1000 μM of ASA treatments.
Canonical pathway | 200 μM | 500 μM | 1000 μM |
---|---|---|---|
TREM1 signaling | −2.0 | −2.1213 | −2.1106 |
Role of pattern recognition receptors in recognition of bacteria and viruses | N/A | −2.3333 | −3.5000 |
Growth hormone signaling | N/A | −2.2361 | −2.6458 |
Production of nitric oxide and reactive oxygen species in macrophages | N/A | −2.7136 | −2.13200 |
Interferon signaling | N/A | −2.000 | −2.44949 |
NF-κB signaling | N/A | −2.333333 | −2.0000 |
Renin-angiotensin signaling | N/A | −1.6667 | −2.3238 |
Colorectal cancer metastasis signaling | N/A | −1.9415 | −2.0412 |
Activation of IRF by cytosolic pattern recognition receptors | N/A | −1.6330 | −2.12132 |
Thrombopoietin signaling | N/A | −1.6330 | −2.1213 |
CDK5 signaling | 0.0 | −2.000 | −1.73205 |
Acute myeloid leukemia signaling | N/A | −2.1213 | −1.5076 |
Protein kinase A signaling | N/A | −1.14708 | −2.3591 |
Agrin interactions at neuromuscular junction | 0.0 | 2.23607 | 1.1339 |
EIF2 signaling | 0.0 | N/A | −2.8402 |
Role of IL-17F in allergic inflammatory airway diseases | N/A | N/A | −2.2361 |
Inhibition of angiogenesis by TSP1 | N/A | N/A | 2.23607 |
Role of RIG1-like receptors in antiviral innate immunity | 0.0 | N/A | −2.2360 |
Regulation of cellular mechanics by calpain protease | 0.0 | N/A | 2.0000 |