Table 4 Brain regions associated with crossmodal interaction

From: Brain mechanisms of oral multisensory processing related to oral health: a systematic review of neuroimaging findings

Group 1: Two modalities of oral sensorimotor processing

Study

Modalities

Design

M1

M2

Basal ganglia

Cere-bellum

S1

S2/ RO

PPC

Olfactory

Visual

Insula

CC

PFC

Narita 2023

sensori-motor

somato-sensory

C

      

R/Lb

 

B

   

Ishii 2023

sensori-motor

somato-sensory

F

      

Bc

 

B

   

Henderson

noxious

sensori-motor

F

L

   

L

    

R

 

R

Hort 2016

gustatory

somato-sensory

F

R

B

  

B

B

R

     

Okamoto 2009

gustatory

sensori-motor

C

B

   

B

       

Group 2: One unimodality of oral sensorimotor processing and one non-oral modality

Study

Modalities

Design

M1

M2

Basal ganglia

Cere-bellum

S1

S2/ RO

PPC

Olfactory

Visual

Insula

CC

PFC

Schumann-Werner 2023

somato-sensory

somato-sensory

C

      

Lc

 

L

   

Suen 2023

gustatory

olfactory

D

R

R

B

B

B

R

 

L

 

R

L

R

Kagawa 2014

somato-sensory

visual

B

      

L

 

B

   

Eldeghaidy 2011

gustatory

olfactory

G

 

R

  

R

R

B

 

R

L

B

B

Etzel 2008

auditory

sensori-motor

  

B

          

Schulz 2003

somato-sensory

auditory

E

    

Bd

       

Group 3: Two non-oral modalities

Study

Modalities

Design

M1

M2

Basal ganglia

Cere-bellum

S1

S2/ RO

PPC

Olfactory

Visual

Insula

CC

PFC

Yamaguchi 2014

visual

sensori-motor

G

L

           

Hilbert 2014a

visual

auditory

B

  

R

      

B

 

L

  1. CC anterior/mid-cingulate cortex, M1 primary motor cortex, M2 secondary motor cortex, including the supplementary motor area, PFC prefrontal cortex, PPC posterior parietal cortex, including the superior and inferior parietal lobules and the supramarginal gyrus, RO Rolandic area, S1 primary somatosensory cortex, S2 secondary somatosensory cortex.
  2. aThe findings revealed the increased activation in patients with dental phobia compared to healthy controls.
  3. bPPC activation was found at the right and the left hemispheres for the food size condition and the food hardness condition, respectively.
  4. cIn Fig. 3 only difference at the visual cortex was displayed.
  5. dThe effect was more pronounced in the trumpeters compared to non-musicians.