Table 1 Characteristics of the included studies.

From: Occlusal vs non-occlusal modality of the loading protocol for oral implants in partially edentulous patients: a systematic review and meta-analysis

First author, year, country

Study design (level of evidence - risk of bias)

Population

Groups

Implant site

Implant prosthesis span

Follow-up (months)

Alassah et al., 2022, Syria

Double blind splitmouth randomised controlled trial (II-low)

Implants: 24

Males: 2

Females: 7

Age: 51 ±  12.6

Implants: 12

Protocol: Early non-occlusal loading

vs

Implants: 12

Protocol: Early occlusal loading

Mandibular Posterior

NR

12

Vogl et al., 2019, Austria

Single blind randomised controlled trial (II-low)

Implants: 19

Males: 7

Females: 12

Age: 54  ±  11.9 (33–70)

Implants: 11

Protocol: Immediate non-occlusal loading

vs

Implants: 8

Protocol: Immediate occlusal loading

Mandibular Posterior

Combination (both single crowns and short bridges)

36

Esposito et al., 2018, Italy

Single blind randomised controlled trial (II- moderate)

Implants: 40

Males: 19

Females: 21

Age: 43.4 (18–65)

Implants: 20

Protocol: Immediate non-occlusal loading

vs

Implants: 20

Protocol: Immediate occlusal loading

Mandibular & Maxillary Posterior

Single-unit crown

36

Degidi et al., 2010, Italy

Single blind randomised controlled trial (II-moderate)

Implants: 100

Males: NR

Females: NR

Age: 45.1 ± 9.1

Implants: 50

Protocol: Immediate non-occlusal loading

vs

Implants: 50

Protocol: Immediate occlusal loading

Mandibular Posterior

Single-unit crown

36

Cannizzaro et al., 2010, Italy

Multi-centre single blind randomised controlled trial (II-low)

Implants: 35

Males: 17

Females: 23

Age: 38.5 (18–55)

Implants: 18

Protocol: Immediate non-occlusal loading

vs

Implants: 17

Protocol: Immediate occlusal loading

Mandible & Maxilla

Single-unit crown

12

Degidi et al., 2009, Italy

Single blind randomised controlled trial (II-low)

Implants: 60

Males: 27

Females: 33

Age: 31.5 ± 11.8 (18–55)

Implants: 30

Protocol: Immediate non-occlusal loading

vs

Implants: 30

Protocol: Immediate occlusal loading

Maxillary Anterior

Multi-unit bridge

36

Lindeboom et al., 2006, Netherlands

Randomised controlled trial (II-moderate)

Implants: 50

Males: 17

Females: 31

Age: 42.3 ± 13.1 (19–78)

Implants: 25

Protocol: Immediate non-occlusal loading

vs

Implants: 25

Protocol: Immediate occlusal loading

Maxillary Anterior

Single-unit crown

12

Appleton et al., 2004, Taiwan

Randomised controlled trial (II-high)

Implants: 20

Males: NR

Females: NR

Age: NR

Implants: 10

Protocol: Delayed progressive (non-occlusal loading)

vs

Implants: 10

Protocol: Delayed occlusal loading

Maxillary Posterior

Single-unit crown

12

  1. A table showing a summary of the characteristics of each included study in this review.
  2. NR Not reported