Fig. 5 | Blood Cancer Journal

Fig. 5

From: CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles

Fig. 5

Differential expression of erythroid and megakaryocyte regulators in CALR-mutated vs. JAK2V617F-positive ET. a The histogram shows the differential expression between CALR-mutated vs. JAK2V617F-positive samples of erythroid and megakaryocyte regulators and markers. The green block indicates a decreased expression, while the red block indicates an increased expression in the pairwise comparison CALR-mutated vs. JAK2V617F-positive ET. b Regulatory networks showing the predicted mRNA–miRNA interactions identified by IPA’s miRNA Target Filter. Green and red colors indicate genes/miRNA down- and upregulated, respectively, in the pairwise comparison CALR-mutated vs. JAK2V617F-positive ET

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