Fig. 6 | Blood Cancer Journal

Fig. 6

From: CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles

Fig. 6

Differential expression of genes involved in platelet activation in CALR-mutated vs. JAK2V617F-positive ET. a Thrombin and RhoA signaling in CALR-mutated vs. JAK2V617F-positive ET. The network also shows the predicted mRNA–miRNA interactions identified by IPA’s miRNA Target Filter. Green and red colors indicate genes/miRNA down- and upregulated, respectively, in the pairwise comparison CALR-mutated vs. JAK2V617F-positive ET. b Box plot shows the increased expression level of THBD in CALR-mutated ET samples

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