Table 3 Univariate and Multivariate analysis of thrombosis-free survival among 587 patients with PV

From: Risk factors for arterial versus venous thrombosis in polycythemia vera: a single center experience in 587 patients

All thrombosis

Univariate analysis

Multivariate analysis

Prior thrombotic events

HR 1.8, CI:1.2–2.6, p = 0.002

HR 1.9, CI: 1.2–2.9, p = 0.03

Leukocytosis (WBC ≥ 11 × 109/L)

HR 1.4, CI: 0.9–2.1, p = 0.03

HR 1.3, CI: 0.9–2.0, p = 0.03

Arterial thrombosis

  

Prior arterial events

HR 3.1, CI: 1.9–4.9, p < 0.0001

HR 2.7, CI:1.7–4.5, p < 0.0001

Hyperlipidemia

HR 2.2, CI:1.4–3.6, p = 0.001

HR 1.8, CI:1.1–2.9, p = 0.03

Hypertension

HR 1.7, CI: 1.1–2.6, p = 0.02

NS, p = 0.1

Venous thrombosis

  

Prior venous events

HR 2.1, CI:1.0–4.7, p = 0.04

HR 2.2, CI: 0.9–4.9, p = 0.05

Leukocytosis (WBC ≥ 11 × 109/L)

HR 2.1, CI: 1.1–3.9, p = 0.0009

HR 2.0, CI:1.1–3.8, p = 0.002

Major hemorrhage

HR 4.7, CI: 1.9–11.0, p = 0.0004

HR 3.4, CI:1.2–9.7, p = 0.02

  1. WBC white blood count, L liter, PV polycythemia vera
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