Table 3 Cox regression analysis

From: Real-world data on prognosis and outcome of primary plasma cell leukemia in the era of novel agents: a multicenter national study by the Greek Myeloma Study Group

Variable

p

HR

95% CI

Univariate cox regression analysis

   

ECOG

0.003

  

AGE ≥ 65

0.02

0.49

0.26–0.92

LDH baseline ≥ 300 U/L

0.008

0.41

0.2–0.7

Bortezomib-based regimens (first line)

0.03

0.46

0.22–0.9

Bortezomib-based regimens + ASCT (first line)

0.01

0.38

0.2–0.8

ASCT

0.01

0.40

0.2–0.8

≥VGPR

0.009

0.40

0.20–0.8

Multivariate cox regression analysis

   

LDH baseline ≥ 300 U/L

0.03

0.45

0.2–0.9

≥VGPR

0.01

0.39

0.2–0.8

  1. ECOG Eastern Cooperative Oncology Group, LDH lactate dehydrogenase, vgPR very good partial response, ASCT autologous stem cell transplantation, HR hazard ratio
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