Table 1 Patient characteristics

From: Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma

Patients (N)

72

Gender

 

 Male

37 (51.4%)

 Female

35 (48.6%)

Age

 

 Median

70

 Range

41–88

Ig subtype

 

 IgG

45 (62.5%)

 IgA

17 (23.6%)

 BJP

7 (9.7%)

 IgD

1 (1.4%)

 NA

2 (2.8%)

ISS stage

 

 I

24 (33.3%)

 II

23 (32%)

 III

25 (34.7%)

Hb

 

 <10 gr/dl

30 (41.7%)

Creatinine

 

 >UNL

20 (27.8%)

 ≥2 mg/dl

12 (16.7%)

LDH

 

 >240 U/L

9 (12.5%)

Osteolysis

 

 Present

53 (73.6%)

Bone disease

 

 Stage A

19 (26.4%)

 Stage B

21 (29.2%)

 Stage C

32 (44.4%)

MRI marrow infiltration pattern

 

 Normal

15 (20.8%)

 Focal

32 (44.4%)

 Diffuse

25 (34.7%)

Calcium (albumin adjusted)

 

 ≤10.1 mg/dl

47 (65.3%)

 10.2–11.5 mg/dl Grade I

19 (26.4%)

 11.5–12.5 mg/dl Grade II

4 (5.5%)

 12.5–13.5 mg/dl Grade III

2 (2.8%)

 >13.5 mg/dl Grade IV

0

  1. BJP Bence Jones Proteinuria, NA not available, UNL upper normal limit, ISS Multiple Myeloma International Staging System, Hb hemoglobin, LDH lactate dehydrogenase, MRI magnetic resonance imaging
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