Table 2 Clinical trial and patient characteristics

From: Disease and outcome disparities in multiple myeloma: exploring the role of race/ethnicity in the Cooperative Group clinical trials

 

N = 2896

Percentage (%)

Clinical trial characteristic

 Enrollment year

1988–1991

591

20.4

1992–2001

1057

36.5

2002–2011

1248

43.1

 Novel agenta utilized

Yes

1087

37.5

No

1809

62.5

 Stem cell transplant utilized

Yes

918

31.7

No

1978

68.3

 Duration of treatment

Fixed duration

607

21.0

Treatment to progression

2289

79.0

Patient characteristic

  

 Race-ethnicity

Non-Hispanic White

2373

81.9

Non-Hispanic African Americans

392

13.5

Non-Hispanic other

55

1.9

Hispanic

76

2.6

 Age

<70 years

2195

75.8

≥70 years

701

24.2

 Gender

Male

1693

58.5

Female

1203

41.5

 International Staging System

ISS I–II

1733

71.4

ISS III

694

28.6

Missing

469

 

 ECOG performance status

PS = 0

1006

35.0

PS > 0

1869

65.0

Missing

21

 

 Hemoglobin

Hb > 10 g/dL

1750

60.6

Hb ≤ 10 g/dL

1136

39.4

Missing

10

 

 Lytic lesions

LL absent

1040

36.1

LL present

1838

63.9

Missing

18

 

 Calcium

Ca ≤ 12 mg/dL

2759

96.2

Ca > 12 mg/dL

109

3.8

Missing

28

 

 Creatinine

Cr < 2 mg/dL

2238

86.8

Cr ≥ 2 mg/dL

340

13.2

Missing

318

 
  1. aNovel agent = proteasome inhibitors or immunomodulatory drugs