Fig. 2: CNV analysis in plasma and tumor. | Blood Cancer Journal

Fig. 2: CNV analysis in plasma and tumor.

From: Non-invasive monitoring of diffuse large B-cell lymphoma by cell-free DNA high-throughput targeted sequencing: analysis of a prospective cohort

Fig. 2

a Boxplot representation of mean VAF (upper panel) or ctDNA amount (lower panel) according to the detection of the CNVs in the plasma samples (neg = negative and pos = positive). The dashed blue lines show the thresholds of detection for CNVs in cfDNA, corresponding to 13.4% for the mean VAF and 1630 hGE/mL for ctDNA. b Example of CNVs from patient #5 in tumor (upper panel) and plasma (lower panel) showing the concordance of the two results when cfDNA of tumoral origin is abundant

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