Fig. 2: Aberrant AS scores among MDS patients. | Blood Cancer Journal

Fig. 2: Aberrant AS scores among MDS patients.

From: The prognostic significance of global aberrant alternative splicing in patients with myelodysplastic syndrome

Fig. 2

Aberrant AS scores in total cohort of 176 MDS patients and 20 normal donors (a), different MDS subgroups according to the FAB classification (b), 2016 WHO classification (c), and mutation status in splicing factor (SF) genes and epigenetic (Epi) genes (d). SF genes include four genes: SF3B1, U2AF1, SRSF2, and ZRSR2. Epigenetic genes include six genes: TET2, ASXL1, DNMT3A, EZH2, IDH1 and IDH2. SF(+): at least one splicing factor gene mutation; Epi(+): at least one epigenetic gene mutation; SF(-): no splicing factor gene mutation; Epi(-): no epigenetic gene mutation; • Dots: mild outlier; * Stars: extreme outlier; bold horizontal lines: median

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