Table 1 Demographic and hematological data parameters in CMML patients, patients with reactive monocytosis, and patients with non-CMML malignancies

From: Multicenter validation of the flow measurement of classical monocyte fraction for chronic myelomonocytic leukemia diagnosis

 

Total CMML

CMML-0

CMML-1

CMML-2

Reactive monocytosis

Non-CMML malignancies

Patients, n (%)

47 (100)

14 (30)

26 (55)

7 (15)

23 (100)

16 (100)

Age, years

75 ± 13

78 ± 8

74 ± 15

73 ± 13

63 ± 23

76 ± 11

M/F (sex ratio)

30/17 (1.8)

8/6 (1.3)

17/9 (1.9)

5/2 (2.5)

17/6 (2.8)

9/7 (1.3)

CBC, n (%)

40 (85)

13 (93)

23 (88)

6 (86)

18 (78)

14 (88)

 Hemoglobin, g/dL

11.5 ± 2.1

12.0 ± 2.3

11.5 ± 2.1

10.6 ± 1.7

11.8 ± 2.4

10.2 ± 1.9

 Platelets, x109/L

156 ± 115

144 ± 128

167 ± 120

138 ± 64

315 ± 157

338 ± 258

 WBC, x109/L

18.9 ± 26.8

15.3 ± 13.6

15.8 ± 16.4

38 ± 60

27.6 ± 47.2

20.9 ± 18.7

 Neutrophils, x109/L

10.5 ± 14.9

9.2 ± 7.7

8.8 ± 9.8

19.7 ± 33

17.3 ± 26.4

13.6 ± 14.3

 Monocytes, x109/L

3.9 ± 3.2

3.2 ± 2.6

3.7 ± 3.11

5.7 ± 4.4

4.3 ± 10.3

2.5 ± 2.0

 Monocytes, %

26.0 ± 10.4

23.2 ± 7.5

27.6 ± 11.3

25.4 ± 11.2

15.1 ± 7.7

14.2 ± 8.6

  1. All parameters are mean ± standard deviation. CMML patients were subdivided into three groups, CMML-0, CMML-1, and CMML-2, according to the WHO classification2. Non-CMML malignancy patients were six myelodysplastic syndromes, two chronic myeloid leukemias, two myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis, one essential thrombocythemia, one non-Hodgkin lymphoma, two malignant blood diseases with JAK2 mutation, and eventually two non-CMML malignancies unspecified by centers