Fig. 1: Clonality and co-occurrence of copy number alterations in MM.
From: Deciphering the chronology of copy number alterations in Multiple Myeloma
Oncoplots showing the clonality level for CNAs (rows) in each patient (columns) at diagnosis for two aneuploidy groups: a HMM and b NHMM. The clonality level of each event is categorized from clonal (dark red) to low subclonal (dark blue). Horizontal bars on the right indicate the proportion of clonal (purple) and all-subclonal-combined (pink) events for each alteration. Bar plots on top show the total number of genomic events for each patient; again, clonal events are purple, and subclonal events are pink. The bottom three rows annotate translocation detected by FISH (blue, yellow, and white colors show detected translocations, no translocation and missing data, respectively). Our classifications of HMM and NHMM patients into subgroups based on copy number patterns are indicated at the bottom in the purple boxes
