Fig. 1: Inducing ex vivo erythroid lineage differentiation from MDS patients derived megakaryocytic-erythroid progenitors (MEPs).

a Representative cytospin staining images of erythroid cells derived from MDS patients and healthy donors (HD) cultured for 4 days and 8 days. The cells indicated by red arrows refer to dysplastic erythrocytes, benzidine-positive and β-galactosidase-positive cells, respectively, in MDS patients which suggested the precocity and prematuring aging in erythroid differentiation of MDS. Scale bar = 20 μm. b Cell proliferation curve was drawn according to cell counts at each stage.