Table 2 Patient disposition based on cytogenetic risk* status.
Standard risk | High risk† | |||
|---|---|---|---|---|
Treatment discontinuation,‡ n (%) | D-Rd (n = 192) | Rd (n = 176) | D-Rd (n = 35) | Rd (n = 34) |
Patients who discontinued treatment | 105 (55) | 148 (84) | 26 (74) | 31 (91) |
Reason for discontinuation | ||||
Progressive disease | 57 (30) | 104 (59) | 17 (49) | 25 (74) |
Adverse event | 28 (15) | 22 (13) | 7 (20) | 4 (12) |
Noncompliance with study drug§ | 7 (4) | 4 (2) | 0 | 2 (6) |
Withdrawal by patient | 2 (1) | 8 (5) | 1 (3) | 0 |
Physician decision | 6 (3) | 3 (2) | 1 (3) | 0 |
Death | 3 (2) | 5 (3) | 0 | 0 |
Other | 2 (1) | 2 (1) | 0 | 0 |
