Table 1 Clinical characteristics by group.

From: Somatic copy number gains in MYC, BCL2, and BCL6 identifies a subset of aggressive alternative-DH/TH DLBCL patients

Measurement

Other (Control)

DH/TH

p

Alt-DH/TH

p

N

407 (85.0%)

21 (4.4%)

 

51 (10.6%)

 

Age

  

0.56

 

0.36

 >60

286 (70.3%)

16 (76.2%)

 

39 (76.4%)

 

 ≦60

121 (29.7%)

5 (23.2%)

 

12 (23.6%)

 

Sex

  

0.14

 

0.96

 Male

230 (56.5%)

11 (52.4%)

 

29 (56.9%)

 

 Female

177 (43.5%)

10 (47.6%)

 

22 (43.1%)

 

IPI

  

0.50

 

0.31

 0–1

160 (39.3%)

5 (23.8%)

 

19 (37.3%)

 

 2

99 (24.3%)

6 (28.6%)

 

10 (19.6%)

 

 3

97 (23.8%)

6 (28.6%)

 

18 (35.3%)

 

 4–5

49 (12.0%)

4 (19.0%)

 

4 (7.8%)

 
 

NA = 2

    

Stage

  

0.13

 

0.96

 I–II

185 (45.5%)

6 (28.6%)

 

23 (45.1%)

 

 III–IV

222 (54.5%)

15 (71.4%)

 

28 (54.9%)

 

COO

  

0.01

 

0.24

 ABC-like

151 (37.1%)

3 (14.2%)

 

15 (29.4%)

 

 GCB

160 (39.3%)

16 (76.2%)

 

27 (52.9%)

 

 Unclassified

36 (8.8%)

1 (4.8%)

 

2 (3.9%)

 

 NA

60 (14.7%)

1 (4.8%)

 

7 (13.8%)

 

Cohort

  

0.27

 

0.31

 Mayo

222 (54.6%)

14 (66.7%)

 

24 (47.1%)

 

 Chapuy et al.

185 (45.4%)

7 (33.3%)

 

27 (52.9%)

 
  1. p chi-square p value, IPI international prognostic index, COO cell-of-origin, ABC-like activated B-cell like, GCB germinal center B-cell, NA not applicable.