Table 2 Summary of systemic AL amyloidosis patients (n = 575) included in subset analyses.
Median (IQR) values at sample collection | |||||
---|---|---|---|---|---|
Description of subgroup | Number of patients | uACR (mg/g) | 24hUP (mg) | dFLC (mg/L) | eGFR—(mL/min/1.73 m2) |
Paired uACR and 24hUP samples <30 days from diagnosisa | 155 | 1362 (87–4311) | 1469 (286–5208) | 242 (89–625) | 62 (39–78) |
Renal involvement at diagnosis | 109 | 3329 (1149–5151) | 3176 (1307–7823) | 174 (70–491) | 63 (38–78) |
eGFR <30 mL/min/1.73 m2 at sample collection | 127 | 2146 (334–5859) | 2663 (654–5996) | 31 (11–169) | 18 (11–25) |
24hUP < 3000 mg/day at sample collection | 466 | 78 (12–743) | 244 (124–1119) | 27 (8–140) | 59 (39–75) |
≥2 paired uACR and 24hUP samples in patients with renal involvement at diagnosisa | 224 | 959 (134–2560)b | 1211 (279–3994)b | 18 (5–72)b | 52 (28–71)b |
uACR, uPCR, and 24hUP available during disease follow-up | 286 | 730 (33–3830) | 1054 (180–4226) | 61 (13–278) | 51 (26–73) |