Fig. 3: CD126-targeted CAR-T cells demonstrated potent in vitro activity against multiple tumor cell lines. | Blood Cancer Journal

Fig. 3: CD126-targeted CAR-T cells demonstrated potent in vitro activity against multiple tumor cell lines.

From: Preclinical development of CD126 CAR-T cells with broad antitumor activity

Fig. 3

Bioluminescence cell killing was performed in ultrachilli-luciferase-expressing cancer cell lines, a RPMI, b HL-60, and c DU145 when co-cultured with either CAR-T or mock T cell at effector-to-target ratios of 10, 5, 1, 0.2, and 0.1 (n = 12). Percent specific lysis was quantified after 16 hours of incubation. Two-way ANOVA and multiple comparison test. n.s. Not significant. **P < 0.01, ***P < 0.001, and ****P < 0.0001.

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