Fig. 3: Transcriptomic expression analysis of small B-cell lymphoma. | Blood Cancer Journal

Fig. 3: Transcriptomic expression analysis of small B-cell lymphoma.

From: Combining gene expression profiling and machine learning to diagnose B-cell non-Hodgkin lymphoma

Fig. 3

a Two-dimensional Principal Component Analysis map computed on small cell lymphoma cases, including follicular lymphoma (orange) and other small cell lymphoma (blue) cases, for the 137 markers included in the panel. The expression of the 40 most discriminatory markers is plotted. b Volcano plots computed on follicular lymphoma (orange) and other small cell lymphoma (blue) cases for the 137 markers included in the panel showing up- or downregulation between these two conditions (absolute log2-fold change >1 and a significant FDR (<0.05)). c Differential expression of a selection of GCB markers, Tfh markers and various markers of interest in the diagnosis of small cell lymphomas. ****p < 10−4 by the Wilcoxon test.

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