Fig. 1: SE induce FOXP3 and CD25 upregulation in malignant cells.
From: Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome
a Malignant cells (SeAx) were cultured alone or in the presence of nonmalignant cells (MF1850) with vehicle (PBS), staphylococcal enterotoxins (SE), or with either a SE-positive (SA sup A) or SE-negative (SA sup B) supernatant from clinical S. aureus isolates for 24h. Contour plots show gated malignant cells. b Malignant cells (SeAx) were cultured alone or in the presence of nonmalignant cells (MF1850) with vehicle (PBS) or with a SE-positive supernatant from a clinical S. aureus isolate (SA sup A) for 72h. Contour plots show gated malignant cells. c Malignant cells (SeAx) and nonmalignant cells (MF1850) were cultured alone or in the presence of nonmalignant cells and malignant cells, respectively, with either vehicle (PBS) or SEA for 48h. Contour plots show gated malignant cells in upper row and nonmalignant cells in bottom row.
