Table 1 Assessment of haematological response pre- and post-renal transplantation and its impact on overall survival.

From: The impact and importance of achieving a complete haematological response prior to renal transplantation in AL amyloidosis

 

Pre-Renal Transplantation

Post-Renal Transplantation

 

OS from renal transplant

P value

OS from renal transplant

P value

CR

123.9 (72.8–143.2) months

0.015

137.8 (113.3–161.6) months

0.0001

VGPR or worse

70.4 (38.4–117.6) months

58.9 (34.4–91.6) months

dFLC >90% reduction

114.4 (47.6–140.4) months

0.602

133.5 (109.3–158.4) months

0.0001

dFLC <90% reduction2

92.9 (63.9–122.1) months

64.4 (41.9–114.1) months

dFLC <10 mg/L

Nil Patients

137.8 (112.4–163.2) months

0.0001

dFLC >10 mg/L14

 

68.5 (58.7–97.3) months

iFLC <20 mg/L

Nil Patients

150.3 (126.2–174.4) months

0.034

iFLC >20 mg/L15

 

84.3 (58.9–103.1) months

  1. SFLC serum free light chain, OS overall survival, CR complete response, VGPR very good partial response, dFLC difference in free light chains, iFLC involved free light chains.
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