Fig. 2: STRING analysis of MSG1 genes and the distribution of drug-associated MSG1 genes within the signalling network. | Blood Cancer Journal

Fig. 2: STRING analysis of MSG1 genes and the distribution of drug-associated MSG1 genes within the signalling network.

From: Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma

Fig. 2

The red dotted frame highlights the “core-network” of 34 genes and the red circles depict drug-associated genes—according to the Drug Gene Interaction Database (DGIdb)—within the core network (n = 10) (A). Distribution of drug-associated MSG1 genes (26/241) among MSG1 MM and their possible association with cancer according to the literature (for reference details, see Supplementary References). The blue colour highlights the 10 drug-associated core-network genes that were highlighted by red circles in Figure 2A (B). SF sample frequency, PF patient frequency, mut mutation.

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