Table 2 Association between single SNPs and MM risk.

SNP	Gene	Allele	MAF^a	EA^a	Allelic model^b			Codominant model^c
SNP	Gene	M/m	MAF^a	EA^a	HR¹	95% CI¹	P_value	HR_Het	95% CI	P_value	HR_Hom	95% CI	P_value
rs11125529	ACYP2	C/A	0.11	A	0.99	0.86–1.16	0.994	1.10	0.92–1.31	0.299	0.63	0.37–1.07	0.093
rs6772228	PXK	T/A	0.04	T	0.81	0.62–1.07	0.121	0.75	0.50–0.99	0.048	1.91	0.43–8.32	0.389
rs10936599	TERC	C/T	0.24	C	0.79	0.70–0.90	1.72 × 10⁻⁴	0.84	0.72–0.98	0.027	0.55	0.39–0.76	2.87 × 10⁻⁴
rs7675998	NAF1	G/A	0.24	G	0.94	0.83–1.06	0.321	0.84	0.73–0.98	0.029	1.15	0.82–1.60	0.402
rs2736100	TERT	A/C	0.5	C	1.07	0.96–1.18	0.223	1.07	0.89–1.28	0.479	1.14	0.92–1.39	0.223
rs9420907	OBFC1	A/C	0.13	C	1.17	1.03–1.35	0.020	1.32	1.12–1.55	7.78 × 10⁻⁴	0.88	0.57–1.35	0.556
rs3027234	CTC1	C/T	0.22	C	0.89	0.79–1.00	0.054	0.97	0.83–1.13	0.669	0.65	0.47–0.90	0.009
rs8105767	ZNF208	A/G	0.28	G	1.14	1.02–1.27	0.022	1.05	0.90–1.21	0.559	1.46	1.12–1.90	0.005
rs412658	ZNF676	C/T	0.35	T	1.01	0.91–1.12	0.866	1.02	0.88–1.18	0.826	1.01	0.81–1.27	0.920
rs6028466	DHX35	G/A	0.07	A	1.23	1.08–1.50	0.042	1.25	1.00–1.55	0.048	1.33	0.55–3.15	0.505
rs755017	ZBTB46	A/G	0.12	G	1.10	0.93–1.29	0.235	1.05	0.88–1.25	0.609	1.61	0.88–2.93	0.120

^aMAF minor allele frequency, EA effect allele, allele associated with longer telomere length, OR odds ratio, 95% CI 95% coefficient interval.
^bAllelic model: M vs. m, common allele vs. rare allele.
^cCodominant model: Mm vs. MM, heterozygous carriers vs. common homozygous, mm vs. MM, rare homozygous vs. common homozygous.

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