Table 3 Association between teloscore and MM risk.

From: Genetically determined telomere length and multiple myeloma risk and outcome

Type of score

Quintiles

Controls

Cases

Total

OR

95% CI

Pvalue

Unweighted, subjects with 100% call rate

1

342

438

780

1.00

Ref.

2

250

344

594

1.03

0.81–1.31

0.788

3

226

327

553

1.18

0.93–1.51

0.178

4

180

293

473

1.32

1.02–1.71

0.032

5

209

367

576

1.36

1.07–1.73

0.013

Continuousa

1207

1769

2976

1.09

1.03–1.15

2.53 × 10−3

Unweighted scaled, all subjects

1

478

522

1000

1.00

Ref.

2

356

449

805

1.09

0.88–1.34

0.422

3

338

448

786

1.25

1.01–1.55

0.037

4

252

440

692

1.59

1.28–1.99

4.17 × 10−5

5

317

548

865

1.58

1.28–1.94

1.93 × 10−5

Continuousa

1741

2407

4148

1.14

1.08–1.19

1.89 × 10−7

Weighted, subjects with 100% call rate

1

244

293

537

1.00

Ref.

2

248

315

563

1.02

0.78–1.32

0.905

3

234

363

597

1.26

0.96–1.63

0.085

4

241

387

628

1.35

1.04–1.75

0.022

5

240

411

651

1.39

1.08–1.80

0.011

Continuousa

1207

1769

2976

1.10

1.04–1.16

1.20 × 10−3

Weighted scaled, all subjects

1

356

361

717

1.00

Ref.

2

342

386

728

1.01

0.79–1.27

0.940

3

348

493

841

1.29

1.03–1.62

0.026

4

348

546

894

1.49

1.19–1.86

4.80 × 10−4

5

347

621

968

1.69

1.36–2.11

2.97 × 10−6

Continuousa

1741

2407

4148

1.15

1.09–1.21

1.07 × 10−8

  1. aThe estimate measures the increase in risk associated with each increase of one quintile.