Table 3 Association between teloscore and MM risk.
From: Genetically determined telomere length and multiple myeloma risk and outcome
Type of score | Quintiles | Controls | Cases | Total | OR | 95% CI | Pvalue |
---|---|---|---|---|---|---|---|
Unweighted, subjects with 100% call rate | 1 | 342 | 438 | 780 | 1.00 | — | Ref. |
2 | 250 | 344 | 594 | 1.03 | 0.81–1.31 | 0.788 | |
3 | 226 | 327 | 553 | 1.18 | 0.93–1.51 | 0.178 | |
4 | 180 | 293 | 473 | 1.32 | 1.02–1.71 | 0.032 | |
5 | 209 | 367 | 576 | 1.36 | 1.07–1.73 | 0.013 | |
Continuousa | 1207 | 1769 | 2976 | 1.09 | 1.03–1.15 | 2.53 × 10−3 | |
Unweighted scaled, all subjects | 1 | 478 | 522 | 1000 | 1.00 | — | Ref. |
2 | 356 | 449 | 805 | 1.09 | 0.88–1.34 | 0.422 | |
3 | 338 | 448 | 786 | 1.25 | 1.01–1.55 | 0.037 | |
4 | 252 | 440 | 692 | 1.59 | 1.28–1.99 | 4.17 × 10−5 | |
5 | 317 | 548 | 865 | 1.58 | 1.28–1.94 | 1.93 × 10−5 | |
Continuousa | 1741 | 2407 | 4148 | 1.14 | 1.08–1.19 | 1.89 × 10−7 | |
Weighted, subjects with 100% call rate | 1 | 244 | 293 | 537 | 1.00 | — | Ref. |
2 | 248 | 315 | 563 | 1.02 | 0.78–1.32 | 0.905 | |
3 | 234 | 363 | 597 | 1.26 | 0.96–1.63 | 0.085 | |
4 | 241 | 387 | 628 | 1.35 | 1.04–1.75 | 0.022 | |
5 | 240 | 411 | 651 | 1.39 | 1.08–1.80 | 0.011 | |
Continuousa | 1207 | 1769 | 2976 | 1.10 | 1.04–1.16 | 1.20 × 10−3 | |
Weighted scaled, all subjects | 1 | 356 | 361 | 717 | 1.00 | — | Ref. |
2 | 342 | 386 | 728 | 1.01 | 0.79–1.27 | 0.940 | |
3 | 348 | 493 | 841 | 1.29 | 1.03–1.62 | 0.026 | |
4 | 348 | 546 | 894 | 1.49 | 1.19–1.86 | 4.80 × 10−4 | |
5 | 347 | 621 | 968 | 1.69 | 1.36–2.11 | 2.97 × 10−6 | |
Continuousa | 1741 | 2407 | 4148 | 1.15 | 1.09–1.21 | 1.07 × 10−8 |