Table 4 Association between individual SNPs and MM OS, adjusted by stage (Durie-Salmon).

SNP	Gene	Allele	MAF^a	EA^a	Allelic model^b			Codominant model^c
SNP	Gene	M/m	MAF^a	EA^a	HR^a	95% CI^a	P_value	HR_Het	95% CI	P_value	HR_Hom	95% CI	P_value
rs11125529	ACYP2	C/A	0.11	A	0.90	0.71–1.13	0.369	0.89	0.68–1.16	0.391	0.59	0.37–1.93	0.710
rs6772228	PXK	T/A	0.04	T	1.30	0.89–1.89	0.165	1.18	0.78–1.75	0.426	4.51	1.06–19.17	0.041
rs10936599	TERC	C/T	0.24	C	1.20	1.00–1.43	0.048	1.23	0.98–1.54	0.066	1.34	0.80– 2.23	0.265
rs7675998	NAF1	G/A	0.24	G	1.18	0.98–1.42	0.080	1.11	0.88–1.40	0.374	1.62	0.99–2.63	0.053
rs2736100	TERT	A/C	0.50	C	1.05	0.89–1.22	0.536	1.02	0.77–1.34	0.879	1.10	0.70–1.49	0.545
rs9420907	OBFC1	A/C	0.13	C	0.96	0.78–1.17	0.724	0.95	0.75–1.20	0.690	0.95	0.51–1.85	0.941
rs3027234	CTC1	C/T	0.22	C	1.03	0.86–1.23	0.726	1.00	0.79–1.25	0.993	1.15	0.71–1.83	0.559
rs8105767	ZNF208	A/G	0.28	G	1.01	0.85–1.19	0.913	1.06	0.84–1.32	0.612	0.95	0.62–1.42	0.799
rs412658	ZNF676	C/T	0.35	T	0.98	0.83–1.15	0.847	1.01	0.80–0.25	0.943	0.95	0.66–1.35	0.763
rs6028466	DHX35	G/A	0.07	A	1.15	0.86–1.52	0.350	1.10	0.78–1.54	0.562	1.58	0.58–4.27	0.369
rs755017	ZBTB46	A/G	0.12	G	0.86	0.67–1.09	0.216	0.92	0.70–1.20	0.559	0.44	0.14–1.37	0.158

^aMAF minor allele frequency, EA effect allele, allele associated with longer telomere length, HR hazard ratio, 95% CI 95% coefficient interval.
^bAllelic model: M vs. m, common allele vs. rare allele.
^cCodominant model: Mm vs. MM, heterozygous carriers vs. common homozygous; mm vs. MM, rare homozygous vs. common homozygous.

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