Table 5 Association between teloscore and MM OS.

From: Genetically determined telomere length and multiple myeloma risk and outcome

Type of score	Quintiles	OS adjusted by stage (DS)						OS adjusted by stage (ISS)
Type of score	Quintiles	Alive	Deceased	Total	HR	95% CI	P_value	Alive	Deceased	Total	HR	95% CI	P_value
Unweighted, subjects with 100% call rate	1	158	65	223	1.00	—	Ref.	130	45	175	1.00	—	Ref.
	2	142	52	194	1.11	0.77–1.60	0.564	115	41	156	1.21	0.78–1.85	0.382
	3	134	48	182	0.98	0.67–1.43	0.930	120	36	156	0.92	0.59–1.43	0.726
	4	117	42	159	0.72	0.48–1.07	0.106	164	50	214	0.77	0.51–1.15	0.210
	5	133	43	176	0.84	0.57–1.24	0.393	54	17	71	0.89	0.50–1.56	0.685
	Continuous^a	684	250	934	0.93	0.85–1.01	0.103	583	189	772	0.92	0.82–1.02	0.138
Unweighted scaled, all subjects	1	182	92	274	1.00	—	Ref.	152	71	223	1.00	—	Ref.
	2	174	77	251	1.06	0.78–1.44	0.684	139	56	195	1.07	0.74–1.52	0.716
	3	172	65	237	0.90	0.65–1.24	0.538	154	50	204	0.83	0.57–1.19	0.317
	4	233	94	327	0.84	0.63–1.12	0.251	196	69	265	0.77	0.55–1.08	0.136
	5	109	37	146	0.73	0.49–1.06	0.106	102	33	135	0.73	0.48–1.12	0.154
	Continuous^a	870	365	1235	0.93	0.85–0.99	0.046	743	279	1022	0.91	0.83–0.99	0.037
Weighted, subjects with 100% call rate	1	136	54	190	1.00	—	Ref.	119	37	156	1.00	—	Ref.
	2	141	54	195	1.06	0.72–1.54	0.765	111	48	159	1.27	0.82–1.96	0.268
	3	127	49	176	1.02	0.69–1.50	0.917	116	36	152	0.94	0.59–1.49	0.797
	4	144	44	188	0.72	0.48–1.07	0.108	121	30	151	0.66	0.40–1.07	0.094
	5	136	49	185	0.91	0.61–1.34	0.626	116	38	154	1.01	0.64–1.60	0.933
	Continuous^a	684	250	934	0.94	0.86–1.03	0.198	583	189	772	0.94	0.84–1.04	0.225
Weighted scaled, all subjects	1	168	83	251	1.00	—	Ref.	147	64	211	1.00	—	Ref.
	2	167	78	245	1.06	0.77–1.44	0.722	138	66	204	1.06	0.75–1.50	0.726
	3	173	73	246	0.97	0.70–1.32	0.837	148	51	199	0.86	0.59–1.24	0.426
	4	181	66	247	0.76	0.55–1.05	0.107	158	46	204	0.67	0.45–0.98	0.042
	5	181	65	246	0.81	0.58–1.12	0.210	152	52	204	0.82	0.57–1.19	0.310
	Continuous^a	870	365	1235	0.93	0.86–0.99	0.049	743	279	1022	0.92	0.84–0.99	0.046

^aThe estimate measures the increase in risk associated with each increase of one quintile.

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Table 5 Association between teloscore and MM OS.

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