Fig. 4: Subgroup analyses of overall response rate and progression-free survival.

A shows overall response rate (confirmed partial response or better) by patient demographics and disease characteristics. B shows progression-free survival by patient demographics and disease characteristics. Patients with a partial response or better according to International Myeloma Working Group criteria applying Food and Drug Administration censoring rules were included. Multiple imputations were performed to create 30 datasets; estimates for the analyses were then obtained using Rubin’s rule to combine the individual estimates from each dataset. *Double-class refractory was defined as refractory to an immunomodulatory agent and a proteasome inhibitor. ORR denotes overall response rate, PFS progression-free survival.