Table 4 Cumulative incidence estimates of treatment initiation, transformation to DLBCL before treatment, and death without therapy based on presence or absence of any treatment initiation criteria at diagnosis.
Time from start of W/W | FL status | Likelihood (point estimates) in the next 1 year (95% CI) | Likelihood (point estimates) in the next 2 year (95% CI) | Likelihood (point estimates) in the next 5 year (95% CI) | Likelihood (point estimates) in the next 10 year (95% CI) |
---|---|---|---|---|---|
Total cohort | Transformation | 0.01 (0.00, 0.03) | 0.03 (0.01, 0.05) | 0.06 (0.04, 0.09) | 0.09 (0.06, 0.13) |
Therapy | 0.16 (0.13, 0.20) | 0.26 (0.22, 0.31) | 0.43 (0.38, 0.48) | 0.48 (0.43, 0.54) | |
Death | 0.01 (0.00, 0.03) | 0.02 (0.01, 0.04) | 0.04 (0.03, 0.07) | 0.06 (0.04, 0.10) | |
Any treatment initiation criteria: positive | Transformation | 0.01 (0.00, 0.04) | 0.02 (0.01, 0.06) | 0.06 (0.04, 0.11) | 0.12 (0.07, 0.19) |
Therapy | 0.15 (0.11, 0.21) | 0.27 (0.22, 0.34) | 0.44 (0.37, 0.51) | 0.48 (0.42, 0.56) | |
Death | 0.01 (0.00, 0.04) | 0.02 (0.01, 0.05) | 0.03 (0.02, 0.07) | 0.06 (0.03, 0.12) | |
Any treatment initiation criteria: negative | Transformation | 0.01 (0.00, 0.04) | 0.03 (0.01, 0.07) | 0.06 (0.03, 0.11) | 0.06 (0.03, 0.11) |
Therapy | 0.15 (0.11, 0.21) | 0.24 (0.18, 0.31) | 0.42 (0.35, 0.50) | 0.49 (0.42, 0.57) | |
Death | 0.01 (0.00, 0.04) | 0.03 (0.01, 0.07) | 0.05 (0.03, 0.10) | 0.06 (0.03, 0.12) |